Join the HREBA-CTC as a Board Member:

Seeking Medical Professionals with a Passion for Ethics in Human Research. The Health Research Ethics Board of Alberta – Clinical Trials Committee (HREBA-CTC) is a pivotal regulatory board overseeing clinical trials in Alberta. We are seeking dedicated Board Members to help guide our ethical review and oversight processes.

Role and Responsibilities:

As a Board Member, you will play a crucial role in reviewing clinical trials involving adult and pediatric participants. Your expertise will contribute to ethical decisions impacting community-based/private practice physicians and other healthcare professionals.


A medical degree (MD) and a background in human research.

Meeting Schedule:

Monthly meetings every 2nd Friday at 9:00 a.m. Meeting format (in-person/virtual/hybrid) and duration dependent on the review agenda.


Members receive an honorarium for study reviews and meeting attendance.

Application Process:

To apply, please contact Jacqueline Senych, HREBA Director at

Include your CV and a brief statement of interest.

Board of Record Agreement

As of August 1, 2019, investigators submitting to any of the Health Research Ethics Board of Alberta (HREBA) committees will be required to have an official agreement appointing HREBA as their Board of Record. For investigators conducting research in Alberta through private practice, other community-based organizations (both for and not-for profit), or Universities outside of Alberta, a signed Board of Record Agreement will be required before approval certificates will be released. Click the title above for more information.

Updated Standard Operating Procedures (SOPs)

HREBA has adopted the fourth version (dated May 15, 2023) of the Standard Operating Procedures (SOPs) developed by the Network of Networks (N2) and the Canadian Association of Research Ethics Boards (CAREB).

These SOPs are specific to ethics boards that review human health sciences research. They are compliant with the applicable Canadian and US regulatory and ethics guidance criteria. They provide a model which will facilitate the distribution, adoption and maintenance of a single standard for REBs in Canada.

Use of SOPs also ensures that the ethics board is constituted appropriately and conducts its processes in a way that protects the rights and safety of study participants.

Please note: The Table of Concordance is still be updated and an updated version will be added at a later date.

Click on the heading above for a list of the SOPs and links to the pdf documents.

HREBA’s Three Committees

The three committees of HREBA work together as one board. For a full list of all HREBA members, please click

Cancer Committee »

Cancer Committee »

The HREBA-CC provides ethical review and oversight for all cancer and cancer-related research involving humans (1,2).

Clinical Trials Committee »

Clinical Trials Committee »

The HREBA-CTC provides ethical review and oversight of clinical trials involving humans (1,2), with the exception of cancer, conducted by community-based/private practice physicians or other qualified healthcare professionals.

Community Health Committee »

Community Health Committee »

The HREBA-CHC provides ethical review and oversight of research involving humans (1,2), with the exception of cancer and clinical trials, conducted by community-based investigators and/or organizations (both for and not-for profit). The committee also provides ethical review for non-research projects (e.g. quality improvement, program evaluation) that are of higher risk, involve vulnerable populations, or areas of sensitivity.

(1) Research involving humans includes both adult and pediatric populations, their information and/or samples.

(2) This includes both research that involves or does not involve health information as defined by the Alberta Health Information Act (HIA).


The Institutional Research Information Services Solution

HREBA’s three committees manage all ethics submissions and reviews through the IRISS on-line platform.

If you are already familiar with the committee that you need to submit your ethics applications through, start by registering on IRISS.  Once you have registered you may submit your ethics application online.  If you have questions, contact

IRISS Registration;IRISS LoginIRISS Resource Page

Scheduled maintenance:

Saturdays and Sundays from 12:00 am to 3:00 am

Please ensure you are logged off the system during this time
as work that has not been saved will be lost.

A confirmed and tentative schedule of outages is posted on the IRISS website  

IRISS Updates and Changes Page


Indigenous Land Acknowledgement

We acknowledge the many First Nations, Métis and Inuit who have lived in and cared for these lands for generations and whose presence continues to enrich our community. We are grateful for the traditional Knowledge Keepers and Elders who are still with us today and those who have gone before us. HREBA respectfully acknowledges that we are situated on traditional territory of the Treaty 6, Treaty 7, and Treaty 8 First Nations*; home to Métis Settlements, the Métis Nation of Alberta, and Regions 2, 3 and 4 within the historical Northwest Métis Homeland. We respect the histories, languages, and cultures of First Nations, Métis, and Inuit whose presence continues to enrich our vibrant community. We see value in gathering as community and are reminded of the responsibility we have to one another.

*Specific Treaty 6, 7, and 8, First Nations are: the Blackfoot Confederacy – Kainai, Piikani, and Siksika – the Cree, Dene, Saulteaux, Nakota Sioux, Stoney Nakoda, and the Tsuu T’ina Nation.

For additional information, click here.