The Clinical Trials Committee (CTC) protects the public by enabling scientific and ethical review of research proposals submitted by registered Alberta physicians who are conducting research involving human subjects. The CTC assesses research proposals submitted by registered Alberta physicians, and health professionals, and provides scientific and ethical feedback to investigators.
The CTC must approve each proposal before it can proceed. All research must be in compliance with laws and other requirements for research involving human subjects.

Please note:

  • All new protocols submitted to the HREBA-CTC must be through IRISS.
  • All existing open files have been migrated to IRISS, and are no longer in paper format.  If you are unclear how to proceed, please email the Ethics Coordinator.


External View Access

To assist researchers whose studies also require approvals from Alberta Health Services (AHS) or Covenant Health for the use of their resources for research purposes (e.g., facilities, equipment, staff, patients or their records and systems), the Health Research Ethics Board of Alberta (HREBA) at Alberta Innovates (AI) is allowing AHS and Covenant Health access to the IRISS system.

Access is being granted in order to facilitate applicable organizational approvals. This new agreement will streamline processes and eliminate duplication, resulting in greater efficiency. Please note this does not apply to purchasing AHS lab services for study purposes, as there are separate service provider agreements that are to be completed.  More information is in this document. 



Research studies funded by industry or other for-profit organizations are charged an administration fee for the initial ethics review. Details are found here.


Marcia Escaravage
Ethics Coordinator
HREBA Clinical Trials Committee
Direct: 780-429-7654
Toll free: 1-877-423-5727