The Clinical Trials Committee (CTC) provides ethical review and oversight of non-cancer clinical trials involving humans (adult and pediatric), their information and/or samples, conducted by community-based/private practice physicians or other qualified healthcare professionals. This includes both research that involves or does not involve health information as defined by the Alberta Health Information Act (HIA).

Information on how to submit and manage an ethics application is available in the PAGES menus to the right.

Please note:

  • All new protocols submitted to the HREBA-CTC must be through IRISS.
  • All existing open files have been migrated to IRISS, and are no longer in paper format.  If you are unclear how to proceed, please email
  • Minimal Risk studies such as Phase 4 Observational  Post-Marketing studies or Chart Reviews should be submitted to HREBA – Community Health Community (HREBA-CHC). If you are unsure where to apply please contact


External View Access

To assist researchers whose studies also require approvals from Alberta Health Services (AHS) or Covenant Health for the use of their resources for research purposes (e.g., facilities, equipment, staff, patients or their records and systems), the Health Research Ethics Board of Alberta (HREBA) at Alberta Innovates (AI) is allowing AHS and Covenant Health access to the IRISS system.

Access is being granted in order to facilitate applicable organizational approvals. This new agreement will streamline processes and eliminate duplication, resulting in greater efficiency. Please note this does not apply to purchasing AHS lab services for study purposes, as there are separate service provider agreements that are to be completed.  More information is in this document. 



Research studies funded by industry or other for-profit organizations are charged an administration fee for the initial ethics review. Details are found here.


Contact Information

If you have questions about a specific file, please contact the HREBA coordinator listed as the “REB Admin”. Contact information can be found here.

If you have a general question, please e-mail


Emergency Contact

Jacqueline Senych, HREBA Director
This after hours emergency line is for urgent requests only